赵建国，中国科学院动物研究所研究员，博士生导师，2010年中国科学院引进国外杰出人才，国家杰出青年基金获得者，中国科学院动物研究所器官再生与智造全国重点实验室研究员，大动物遗传修饰研究组组长，中国科学院大学博士研究生导师。近年来以通讯作者（含共同）身份在Sci Adv、 PNAS、Blood、EMBO Mol Med、eLife、Natl Sci Rev、J Mol Cell Biol、Biol Reprod等期刊发表SCI论文50多篇。担任J Mol Cell Biol、J Integr Agr等杂志副主编或者编委会委员。担任中国畜牧兽医学会动物遗传育种学分会副理事长、中国动物学会生殖生物学分会以及中国实验动物学会常务理事等。担任基金委重大项目首席、科技部“863”项目首席科学家、国家重点研发计划项目首席以及国家重点研发计划“生物医用材料研发与组织器官修复替代”重点专项专家组成员、转基因创制生物新品种重大专项科技部评估专家组成员，国家畜禽遗传资源委员会猪专业委员会委员等。在国际国内会议作特邀报告40余次，获得发明专利6项。

赵建国研究员于2003年毕业于东北农业大学，获博士学位；2003至2005年在上海交通大学医学遗传研究所任助理研究员，2005至2007年在美国新奥尔良大学任博士后研究人员；2007至2010年在美国密苏里大学哥伦比亚分校/美国猪资源与研究中心任研究助理教授；2010年8月加入中国科学院动物研究所，任研究组组长。

1. Yang YJ , Zhang Y , Liu Q, Tian SJ , Feng WY, Deng FW, Qin GS , Wang YF * , Zhao JG* .OIVC medium enhances developmental competence in porcine preimplantation embryos. Journal of Integrative Agriculture.2025
2. Wang X , Liu TX , Zhang Y, Xu LW ,Yuan SL ,Cui AL , Guo WW , Wang YF ,  Yang SM*,Zhao JG*.Genetically modified pigs: Emerging animal models for hereditary hearing loss.Zoological Research.2024, 45(2): 284−291
3. Wang Z , Wang Y, Zhang Y, Qin GS , Sun WB , Wang AP, Wang YF * , Zhang GP*, Zhao JG*.On-site detection and differentiation of African swine fever virus variants using an orthogonal CRISPR-Cas12b/Cas13a-based assay.iScience.2024,27
4. Wang XY, Wang Y, Wang Y, Guo YF, Zong RJ, Hu ST, Yue JW, Yao J, Han CS *, Guo JT*,Zhao JG*. Single-cell transcriptomic and cross-species comparison analyses reveal distinct molecular changes of porcine testes during puberty.Communications Biology. 2024,7 (1), 1478
5. Qi YN, Zhang Y, Tian SJ, Zong RJ, Yan XH, Wang Yu, Wang YF *, Zhao JG*. An optimized prime editing system for efficient modification of the pig genome. SCIENCE CHINA Life Sciences. 2023, (66) 2851-2861
6. Ma YJ, Wu BB, Chen YH, Ma S, Wang LY, Han TT, Lin XL, Yang FL, Liu C, Zhao JG*, Li W*. CCDC146 is required for sperm flagellum biogenesis and male fertility in mice. Cellular and Molecular Life Sciences. 2023 Dec 1;81(1):1
7. Dong FC , Wang XG, Huang T , Yin YY, Xiao S, Ma YJ, Wei HF, Wu BB, Zhang RD, Wang LY, Guo XJ, Gao F, Liu C, Liu HB,Zhao JG*,Li W *.CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice. Genes & Disease. 2023.09
8. Qiao CM, He MZ, Wang SM, Jiang XJ , Wang F , Li XJ, Tan S, Chao Z, Xin WS , Gao S , Yuan JL, Li Q, Xu ZC , Zheng XL, Zhao JG*, Liu GL *.Multi-omics analysis reveals substantial linkages between the oral-gut microbiomes and inflamm-aging molecules in elderly pigs. Frontiers in Microbiology. 2023:14
9. Zhao Y, Chen CH ,Pan JL, Lam Sin Man , Shui GH, Yang SL, Wu TW , Yang N, Tao C, Zhao JG*; Wang, YF*. Adipocyte Rnf20 ablation increases the fast-twitch fibers of skeletal muscle via lysophosphatidylcholine 16:0. Cellular and Molecular Life Science.2023:9
10. Song R, Wang Y, Zheng Q, Yao J, Cao C, Wang Y*, Zhao JG*. One-step base editing in multiple genes by direct embryo injection for pig trait improvement. Sci China Life Sci. 2022 Ap;65(4):739-752.
11. Gu P, Hui X, Zheng Q, Gao Y, Jin L, Jiang W, Zhou C, Liu T, Huang Y, Liu Q, Nie T, Wang Y, Wang Y, Zhao JG*, Xu A*. Mitochondrial uncoupling protein 1 antagonizes atherosclerosis by blocking NLRP3 inflammasome-dependent interleukin-1β production. Sci Adv. 2021; 7(50): eabl4024.
12. Song R, Liu K, Wang Y, Qin G, Xiao M, Liu Y, Yang J, Zong R, Yan X, Zheng Q, Zhang H, Hou N, Yao J, Wang X, Wang Y, Zhao JG*, Zhang X*. A NCSTN heterozygous point mutation pig model simulates familial acne inversa and reveals dysregulated cholesterol biosynthesis via the notch-pAMPK-HMGCR pathway. Science Bulletin.2021, 66(23):2343-2346.
13. Liang X, Tao C, Pan J, Zhang L, Liu L, Zhao Y, Fan Y, Cao C, Liu J, Zhang J, Lam SM, Shui G, Jin W, Li W, Zhao JG*, Li K*, Wang Y*. Rnf20 deficiency in adipocyte impairs adipose tissue development and thermogenesis. Protein Cell. 2021, 12(6):475-492.
14. Liu L,Wang Y,Liang X,Wu X,Liu J,Yang S,Tao C,Zhang J,Tian J, Zhao JG*, Wang Y*. Stearoyl-CoA desaturase is essential for porcine adipocyte differentiation. Int J Mol Sci. 2020 Apr 1;21(7): E2446.
15. Zhao JG, Lai L, Ji W, Zhou Q^*. Genome editing in large animals: Current status and future prospects. Natl Sci Rev.2019, 6(3) : 402–420
16. Hai T, Cao C, Shang H, Guo W, Mu Y, Yang S, Zhang Y, Zheng Q, Zhang T, Wang X, Liu Y, Kong Q, Li K, Wang D, Qi M, Hong Q, Zhang R, Wang X, Jia Q, Wang X, Qin G, Li Y, Luo A, Jin W, Yao J, Huang J, Zhang H, Li M, Xie X, Zheng X, Guo K, Wang Q, Zhang S, Li L, Xie F, Zhang Y, Weng X, Yin Z, Hu K, Cong Y, Zheng P, Zou H, Xin L, Xia J, Ruan J, Li H, Zhao W, Yuan J, Liu Z, Gu W, Li M, Wang Y, Wang H*, Yang S*, Liu Z*, Wei H*, Zhao JG*, Zhou Q*, Meng A*. Pilot study of large-scale production of mutant pigs by ENU mutagenesis. Elife. 2017, 6. pii: e26248.
17. Lin J, Cao C, Tao C, Ye R, Dong M, Zheng Q, Wang C, Jiang X, Qin G, Yan C, Li K, Speakman JR, Wang Y*, Jin W*, Zhao JG*. Cold adaptation in pigs depends on UCP3 in beige adipocytes. J Mol Cell Biol. 2017 May 9.
18. Zheng Q, Lin J, Huang J, Zhang H, Zhang R, Zhang X, Cao C, Hambly C, Qin G, Yao J, Song R, Jia Q, Wang X, Li Y, Zhang N, Piao Z, Ye R, Speakman JR, Wang H, Zhou Q, Wang Y, Jin W, Zhao JG*. Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decrease fat deposition and improve thermogenic capacity. Proc Natl Acad Sci U S A. 2017;
19. Zhang Y, Xue Y, Cao C, Huang J, Hong Q, Hai T, Jia Q, Wang X, Qin G, Yao J, Wang X, Zheng Q, Zhang R, Li Y, Luo A, Zhang N, Shi G, Wang Y, Ying H, Liu Z, Wang H, Meng A, Zhou Q, Wei H*, Liu F*, Zhao JG*. Thyroid hormone regulates hematopoiesis via the TR-KLF9 axis. Blood. 2017; 130(20):2161-2170.